Is the Mediterranean Diet Protective Against Alzheimer's Disease?

People who eat a "Mediterranean" diet rich in fruits, vegetables, olive oil, legumes, cereals and fish have a lower risk of developing Alzheimer's disease, U.S. researchers report.

|PIC1|"We have confirmed the association of a Mediterranean diet with Alzheimer's disease," said lead researcher Dr. Nikolaos Scarmeas, an assistant professor of neurology at Columbia University Medical Center in New York.

This benefit does not appear to be due to the diet's effect on blood vessels, Scarmeas added. "The diet could be helping avoid Alzheimer's disease by protection from oxidative stress or by reducing inflammation in the brain," he said.

The report appears in the online October issue of the Archives of Neurology.

For the diet study, Scarmeas's team collected data on almost 2,000 people averaging 76 years of age. Of these, 194 had developed Alzheimer's. The researchers analyzed each person's diet during the previous year and scored the diet based on how closely it followed what's known as the Mediterranean diets. Scores ranged from zero to 9. Higher scores were given for closely following a Mediterranean diet.

People who closely followed that regimen had a significantly lower risk for Alzheimer's disease, the researchers found. For each additional point on the diet score, risk for Alzheimer's was reduced by 19 to 24 percent.

While this evidence does not conclusively prove that a Mediterranean diet actually protects people from developing Alzheimer's disease, Scarmeas believes that the health benefits of the diet are clear.

"It seems that this diet is [health] protective," Scarmeas said. "Taking into account that this diet is protective for other conditions such as coronary heart disease, heart attack, high blood pressure, obesity and a series of cancers, it seems to make sense to follow this diet anyway, and the diet may also protect from Alzheimer's disease."