The Arizona Cardinals will clash with the Detroit Lions on Sunday in three late afternoon games in Week 5 of the NFL 2015 regular season. The Lions are still without a win this season so far, where as the Cardinals suffered their first loss last week to come into Week 5 on 3-1. The game has a scheduled start time of 4.05 p.m. ET and takes place from Ford Field in Detroit, Michigan. The game can be watched on TV on the Fox network or online through live stream via the link below.

The Cardinals will be massive favorites to win today's game; they have scored an average of 39 points per game in recent weeks, where as the Lions have scored just 38 points in total over that same period.

The Lions remain the NFL's only winless team this season, and another defeat today would plunge them to new depths.

Detroit could be on the receiving end of a strong reaction from the Cardinals' offense as well, after Arizona fell to defeat for the first time this season last Sunday. That result was quarterback Carson Palmer's first loss in 10 games, and he will be desperate to return to winning ways today.

Palmer has said following last week's defeat: "I think that sometimes these things are a blessing in disguise, just because I think this team will respond exactly the way it's supposed to. We will come back."

That will go out as a warning to the Lions for today's game, and unless they are at their very best, especially in defense, then today could be a long game for them.

Earlier this week on Thursday Night Football, the Indianapolis Colts and Houston Texans faced off with the Colts claiming a hard earned 27-20 victory.

The story of the night was Andre Johnson, who caught two touchdown passes against his former team to secure the win for the Colts.

Johnson of course spent 12 seasons in the NFL with the Texans before being released by Houston earlier this year in March. Johnson finished the the game with six catches for 77 yards, and ultimately proved the difference between the teams.

The victory meant that the Colts have won a record breaking 16 consecutive AFC South games, the longest such streak in the NFL.

The Colts claimed the win despite losing star quarterback Andrew Luck to injury for the second game in a row. He was replaced by 40 year old veteran Matt Hasselbeck, who was also thought not to be in perfect fitness after missing training just two days before on Tuesday.

Today's big NFL game between the Arizona Cardinals and the Detroit Lions has a scheduled start time of 4.05 p.m. ET and can be watched on TV on the Fox network or online through live stream by clicking here.